ea0090p369 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023
Gatta-Cherifi Blandine
, Mohammedi Kamel
, Cariou Tanguy
, Poitou-Bernert Christine
, Touraine Philippe
, Raverot Gerald
, Brue Thierry
, Chanson Philippe
, Illouz Frederic
, Solange Grunenwald
, Chabre Olivier
, Sonnet Emmanuel
, Cuny Thomas
, Bertherat Jerome
, Czernichow Sebastien
, Frison Eric
, Tabarin Antoine
Background: Hyperphagia leading to craniopharyngioma-related obesity (CRO) is a common and serious sequel of treatments of craniopharyngiomas. The few therapeutic approaches that have been tested until now for the control of eating behaviour and weight have poor efficacy. Glucagon-like peptide-1 (GLP-1) analogues might be an option. Methods: This multicentre, randomised, double-blind superiority trial was conducted in France. Adults with CRO (BMI > 3...